MedPharmRes

About MedPharmRes

The University of Medicine and Pharmacy at Ho Chi Minh City is pleased to announce its first English journal MedPharmRes (Publication permit 121a/GP-BTTTT of March 23, 2017 by the Ministry of Information and Communications of the Socialist Republic of Vietnam). MedPharmRes is proud to be an English open access peer reviewed journal that delivers cutting edge research in various aspects of medicine, pharmacy, dentistry and other health sciences. Currently, the new permit is numbered 52/GP-BTTTT, issued on March 6, 2024.
Review Article

Jun 30, 2025

A mini review on role of macro- and micronutrients in managing intrapancreatic fat deposition

Juyeon Ko, Sukyung Ko, Le Thi Ngoc Anh, Jaelim Cho

MedPharmRes 2025;9(2):141-150.
https://doi.org/10.32895/UMP.MPR.9.2.13

The increasing prevalence of obesity has drawn attention to intra-pancreatic fat deposition (IPFD), a condition associated with metabolic disorders such as type 2 diabetes, chronic pancreatitis, and pancreatic cancer. Although initially linked to general obesity, IPFD is now recognized in non-obese individuals, with its prevalence often underestimated due to the absence in International Classification of Diseases. Chemical shift-encoded magnetic resonance imaging (MRI) has become the preferred method for non-invasive quantification of IPFD, pro...
Review Article

Jun 30, 2025

Biphasic in-vitro maturation: an advancement over traditional in-vitro maturation

Lan N Vuong, Tuong M Ho, Robert B. Gilchrist

MedPharmRes 2025;9(2):151-157.
https://doi.org/10.32895/UMP.MPR.9.2.14

Culture conditions for standard in-vitro maturation (IVM) have remained largely unchanged for more than 50 years and are non-physiological, limiting the success of this form of assisted reproductive technology (ART). Advances in the understanding of oocyte biology have led to the development of biphasic oocyte maturation approaches, such as IVM with a pre-maturation step, exemplified by capacitation IVM (CAPA-IVM). Biphasic IVM protocols consist of two steps: a pre-IVM step (to enhance germinal vesicle oocyte development) and an IVM step. The k...
Original Article

Jun 30, 2025

The self-efficacy in clinical practice among nursing students in Ho Chi Minh City: a cross-sectional study

Loan Thi Chu, Phuong Thu Thi Pham, Anh Phuong Nhat Tran, Lien Ngoc Lieu, Hue Thi Nguyen, Truc Thanh Thai

MedPharmRes 2025;9(2):158-166.
https://doi.org/10.32895/UMP.MPR.9.2.15

Introduction: Self-efficacy plays a crucial role in the academic success and skill development of nursing students. Assessing self-efficacy in clinical practice is essential for implementing early interventions at nursing universities. This study aimed to explore the level of self-efficacy levels and associated factors among nursing students in a Vietnamese nursing institution. Methods: A cross-sectional study was conducted from May to June 2022 with the third- and fourth-year nursing students at University of Medicine and Pharmacy at Ho Chi Mi...
Original Article

Jun 30, 2025

Effectiveness of laser acupuncture combined with physiotherapy in tennis elbow syndrome: a pre-post pilot study

Hung Le Viet Nguyen, Duy Thi Thuy Duong, Huy Chung Ly, Sang Thanh Do

MedPharmRes 2025;9(2):167-179.
https://doi.org/10.32895/UMP.MPR.9.2.16

Introduction: Lateral epicondylitis (LE) syndrome affects 1–3% of adults, and the effectiveness of non-invasive treatments remains unclear. Laser acupuncture (LA) may relieve pain as a less invasive alternative to other treatments, while physical therapy can help reduce stress on the tendons. Therefore, this study aimed to determine the potential effect of combining LA with physical therapy in patients with LE syndrome. Methods: The pilot study used a single group with 30 LE patients, who were treated by LA combined with physiotherapy exercis...
Original Article

Jun 30, 2025

The gastroprotective effect of Ludwigia octovalvis (Jacq) against ethanol-induced gastric ulcers in mice

My-Duyen Thi Chung, Lan-Phuong Thi Le, Ngoc-Hieu Thi Chuong, Minh-Nhut Truong, Duc Phan Nguyen Duong

MedPharmRes 2025;9(2):180-192.
https://doi.org/10.32895/UMP.MPR.9.2.17

Introduction: This study investigated the antioxidant effect in vitro and gastroprotective effect of Ludwigia octovalvis (Jacq) against HCl/ethanol-induced acute gastric ulcers in mice. Methods: The antioxidant activities (AAs) of 96% ethanol and water extracts from L. octovalvis’ aerial parts were assessed using the 2,2-diphenyl-1-picrylhydrazyl assay. Acute toxicity was evaluated in 6-week-old Institute of Cancer Research’s (ICR) male mice, followed by a 7-day oral pretreatment with either the ethanol extract (0.7–1.4 g/kg), water extra...
Original Article

Jun 30, 2025

Assessing physical activity levels and associated factors among pregnant women in Hanoi, Vietnam: a facility-based cross-sectional study

Quy Thi Nhu Nguyen, Cham Linh Tran, Ngọc Ha Me Tran

MedPharmRes 2025;9(2):193-206.
https://doi.org/10.32895/UMP.MPR.9.2.18

Background: Physical activity (PA) during pregnancy offers substantial health benefits for both mothers and fetuses. However, many pregnant women do not meet recommended activity levels. This study aimed to evaluate PA levels and associated factors among pregnant women in Hanoi, Vietnam. Methods: A cross-sectional study was conducted among 234 pregnant women attending prenatal check-ups at Hanoi Obstetrics and Gynecology Hospital from January to May 2024. Data on demographics, clinical history, and pregnancy-related activities were collected us...
Original Article

Jun 30, 2025

A retrospective study of the risk factors for linezolid-induced thrombocytopenia in hospitalized patients

Khue Nguyen Y Ha, Tuyen Thi Thanh Vu, Truc Thi Thuy Nguyen, Hao Quan Nhu Nguyen, Trang Nguyen Doan Dang

MedPharmRes 2025;9(2):207-219.
https://doi.org/10.32895/UMP.MPR.9.2.19

Introduction: Linezolid is widely used to treat multidrug-resistant Gram-positive infections, often at set doses independent of renal impairment. However, a clear exposure-response association has been established for linezolid-induced thrombocytopenia in patients with renal impairment. The purpose of this study is to assess the prevalence of thrombocytopenia and identify the risk factors for linezolid-induced thrombocytopenia in this population. Methods: A retrospective study was conducted in who had taken standard-dose linezolid for at least ...
Original Article

Jun 30, 2025

Apoptosis induction of the rosmarinic acid-loaded mesoporous organosilica nanoparticles on gastric cancer cells

Uyen-Chi Nguyen Le, Kieu-Minh Le, Hoang Anh Vu, Tan Le Hoang Doan

MedPharmRes 2025;9(2):220-231.
https://doi.org/10.32895/UMP.MPR.9.2.20

Introduction: Rosmarinic acid has anticancer properties because it inhibits cell growth and induces apoptosis. However, its stability is significantly diminished in the acidic environment of digestive system. Although encapsulation of rosmarinic acid with nanoscale materials is required to increase its bioavailability, the anticancer activity must be maintained. We have previously synthesized a new form of organosilica nanoparticle that could efficiently load rosmarinic acid in its pores, called as RA@SiNPs. These compounds were hazardous to so...
Original Article

Jun 30, 2025

Fabricating a low-cost 3D printed transparent temporal bone model for anatomy teaching in medical education

Dat Minh Lu, Hien Bui Thu Hoang, Tam Minh Le, Son Trung Huynh, Phuong Thi Mai Ngo, Sang Thanh Bui, Quynh Nhat Nguyen, Linh Le Tran, An Le Pham

MedPharmRes 2025;9(2):232-240.
https://doi.org/10.32895/UMP.MPR.9.2.21

Introduction: The intricate anatomy of the human temporal bone poses challenges for medical students in achieving a comprehensive understanding. Additionally, the avaibility of temporal bones from cadavers is limited, and specimen processing is costly. Therefore, we aimed to describe the process of 3D reconstruction and the manufacturing of an assemblable temporal bone model from computed tomography scan images for anatomical study using cost-effective 3D printing techniques. Methods: The three-part 3D model of the right healthy temporal bone o...
Original Article

Jun 30, 2025

Factors associated with self-care practices in postoperative colorectal cancer patients undergoing chemotherapy

Hung Manh Cao, Tham Duyen Thi Nguyen, Kieu Ngoc Thi Mai, Phuoc Huu Tran, Quynh Nhu Thi Nguyen

MedPharmRes 2025;9(2):241-248.
https://doi.org/10.32895/UMP.MPR.9.2.22

Introduction: Self-care practices are essential for helping patients undergoing adjuvant chemotherapy after colorectal cancer surgery in managing and coping with the common side effects of treatment. However, these practices can be influenced by various factors. Identifying these factors is crucial, as it enables healthcare providers, particularly nurses, to design and implement interventions that can improve patients’ self-care abilities and overall quality of life. Methods: A descriptive analytical cross-sectional study was conducted on 200...
Original Article

Jun 30, 2025

Episiotomy incidence and decision-making factors: a prospective descriptive study at a maternity hospital in Vietnam

Dung Tuan Dao, Hang Thi Phan, Thuong Chi Bui

MedPharmRes 2025;9(2):249-261.
https://doi.org/10.32895/UMP.MPR.9.2.23

Introduction: Episiotomy, a perineal incision performed to expand the birth canal and expedite labor, is typically done based on the birth attendant’s assessment. This study aimed to investigate the incidence of episiotomy in vaginal deliveries and to explore the factors that influence clinical decision-making at Hung Vuong Hospital. Methods: This prospective descriptive study included 384 vaginal delivery cases from labor onset to hospital discharge between March and May 2023. Data on medical history, pregnancy, labor, postpartum details, an...
Original Article

Jun 30, 2025

Assessment of outcomes of emergent stenting in vertebrobasilar occlusion stroke: a single experience in a comprehensive stroke centre

Thang Minh Le, Huy Dao Nhat Nguyen, Tran Thi To Nguyen, Luan Minh Bao Tran

MedPharmRes 2025;9(2):262-271.
https://doi.org/10.32895/UMP.MPR.9.2.24

Introduction: In acute posterior circulation strokes, vertebrobasilar occlusions are typically associated with poorer outcomes than anterior circulation strokes. Previous trials had an overall mortality rate of 37%. However, few studies have addressed the benefit and safety of the emergent stenting in the successful recanalization at these complex occlusions. We studied whether clinical outcomes improved three months after the procedure. Methods: A retrospective analysis of acute vertebrobasilar occlusions patients who received emergent stentin...
Corrigendum

Jun 30, 2025

Corrigendum: Surgical treatment for biliary obstruction in patients with painful chronic pancreatitis and a dilated duct: choledochojejunostomy or biliopancreatic tunneling?

Dai Nga Mai, Quoc Vinh Nguyen, Minh Tri Phan, Tien My Doan

MedPharmRes 2025;9(2):272-273.
https://doi.org/10.32895/UMP.MPR.9.2.25

CURRENT ISSUE: Jun 2025, Vol. 9, No. 2

Review Article A mini review on role of macro- and micronutrients in managing intrapancreatic fat deposition Juyeon Ko, Sukyung Ko, Le Thi Ngoc Anh, Jaelim Cho MedPharmRes 2025;9(2):141-150. https://doi.org/10.32895/UMP.MPR.9.2.13 HTML PDF PubReader	Review Article Biphasic in-vitro maturation: an advancement over traditional in-vitro maturation Lan N Vuong, Tuong M Ho, Robert B. Gilchrist MedPharmRes 2025;9(2):151-157. https://doi.org/10.32895/UMP.MPR.9.2.14 HTML PDF PubReader
Original Article The self-efficacy in clinical practice among nursing students in Ho Chi Minh City: a cross-sectional study Loan Thi Chu, Phuong Thu Thi Pham, Anh Phuong Nhat Tran, Lien Ngoc Lieu, Hue Thi Nguyen, Truc Thanh Thai MedPharmRes 2025;9(2):158-166. https://doi.org/10.32895/UMP.MPR.9.2.15 HTML PDF PubReader	Original Article Effectiveness of laser acupuncture combined with physiotherapy in tennis elbow syndrome: a pre-post pilot study Hung Le Viet Nguyen, Duy Thi Thuy Duong, Huy Chung Ly, Sang Thanh Do MedPharmRes 2025;9(2):167-179. https://doi.org/10.32895/UMP.MPR.9.2.16 HTML PDF PubReader
Original Article The gastroprotective effect of Ludwigia octovalvis (Jacq) against ethanol-induced gastric ulcers in mice My-Duyen Thi Chung, Lan-Phuong Thi Le, Ngoc-Hieu Thi Chuong, Minh-Nhut Truong, Duc Phan Nguyen Duong MedPharmRes 2025;9(2):180-192. https://doi.org/10.32895/UMP.MPR.9.2.17 HTML PDF PubReader	Original Article Assessing physical activity levels and associated factors among pregnant women in Hanoi, Vietnam: a facility-based cross-sectional study Quy Thi Nhu Nguyen, Cham Linh Tran, Ngọc Ha Me Tran MedPharmRes 2025;9(2):193-206. https://doi.org/10.32895/UMP.MPR.9.2.18 HTML PDF PubReader
Original Article A retrospective study of the risk factors for linezolid-induced thrombocytopenia in hospitalized patients Khue Nguyen Y Ha, Tuyen Thi Thanh Vu, Truc Thi Thuy Nguyen, Hao Quan Nhu Nguyen, Trang Nguyen Doan Dang MedPharmRes 2025;9(2):207-219. https://doi.org/10.32895/UMP.MPR.9.2.19 HTML PDF PubReader	Original Article Apoptosis induction of the rosmarinic acid-loaded mesoporous organosilica nanoparticles on gastric cancer cells Uyen-Chi Nguyen Le, Kieu-Minh Le, Hoang Anh Vu, Tan Le Hoang Doan MedPharmRes 2025;9(2):220-231. https://doi.org/10.32895/UMP.MPR.9.2.20 HTML PDF PubReader
Original Article Fabricating a low-cost 3D printed transparent temporal bone model for anatomy teaching in medical education Dat Minh Lu, Hien Bui Thu Hoang, Tam Minh Le, Son Trung Huynh, Phuong Thi Mai Ngo, Sang Thanh Bui, Quynh Nhat Nguyen, Linh Le Tran, An Le Pham MedPharmRes 2025;9(2):232-240. https://doi.org/10.32895/UMP.MPR.9.2.21 HTML PDF PubReader	Original Article Factors associated with self-care practices in postoperative colorectal cancer patients undergoing chemotherapy Hung Manh Cao, Tham Duyen Thi Nguyen, Kieu Ngoc Thi Mai, Phuoc Huu Tran, Quynh Nhu Thi Nguyen MedPharmRes 2025;9(2):241-248. https://doi.org/10.32895/UMP.MPR.9.2.22 HTML PDF PubReader
Original Article Episiotomy incidence and decision-making factors: a prospective descriptive study at a maternity hospital in Vietnam Dung Tuan Dao, Hang Thi Phan, Thuong Chi Bui MedPharmRes 2025;9(2):249-261. https://doi.org/10.32895/UMP.MPR.9.2.23 HTML PDF PubReader	Original Article Assessment of outcomes of emergent stenting in vertebrobasilar occlusion stroke: a single experience in a comprehensive stroke centre Thang Minh Le, Huy Dao Nhat Nguyen, Tran Thi To Nguyen, Luan Minh Bao Tran MedPharmRes 2025;9(2):262-271. https://doi.org/10.32895/UMP.MPR.9.2.24 HTML PDF PubReader
Corrigendum Corrigendum: Surgical treatment for biliary obstruction in patients with painful chronic pancreatitis and a dilated duct: choledochojejunostomy or biliopancreatic tunneling? Dai Nga Mai, Quoc Vinh Nguyen, Minh Tri Phan, Tien My Doan MedPharmRes 2025;9(2):272-273. https://doi.org/10.32895/UMP.MPR.9.2.25 HTML PDF PubReader

MOST READ ARTICLES

Review Article Updated biomarkers for extracellular traps from neutrophil, monocyte, and M1 macrophage in neutrophilic asthma: a narrative review Quoc Quang Luu, Thi Bich Tra Cao, Hae-Sim Park, Duy Le Pham MedPharmRes 2025;9(1):1-16. https://doi.org/10.32895/UMP.MPR.9.1.1 HTML PDF PubReader Last 3 months views: 2533	Case report A case report of COVID-19-associated severe psychotic symptoms and suicidal behavior: a late psychiatric intervention Yen Phi Ho Nguyen, Xuan Manh Bui, Minh Chau Pham, Anh Ngoc Tran, Trung Nghia Tran, Tich Linh Ngo MedPharmRes 2023;7(s3):s12-s15. https://doi.org/10.32895/UMP.MPR.7.3.S12 HTML PDF PubReader Last 3 months views: 2339
Original Article Effects of internet addiction and smartphone addiction on the sleep quality of students of the Faculty of Public Health, University of Medicine and Pharmacy at Ho Chi Minh City in 2023 Minh Quang Lam, Nhat Duyet Pham, Linh Thy Le, Thi Thu Ha Dam MedPharmRes 2025;9(1):62-73. https://doi.org/10.32895/UMP.MPR.9.1.6 HTML PDF PubReader Last 3 months views: 1962	Original article Implementation status of antimicrobial stewardship programs in hospitals: A quantitative analysis study in Ho Chi Minh city, Vietnam Yen Thi Hai Nguyen, Dat Van Truong, Thao Phuong Huynh, Thuong Chi Tang, Chau Van Vinh Nguyen, Thai Minh Tran, Qui Tu Phan, Tien Ngoc Cam Phung, Le Dang Tu Nguyen MedPharmRes 2020;4(2):34-39. https://doi.org/10.32895/UMP.MPR.4.2.5 HTML PDF PubReader Last 3 months views: 1616
Original article Validity of puberty self-report in children and adolescents in Ho Chi Minh City Tam Minh Do, Thanh Van Kim, Huyen Thi Bich Tran, Thanh Thi Kim Tran, Minh Xuan Ngo, Hong Kim Tang MedPharmRes 2020;4(4):33-37. https://doi.org/10.32895/UMP.MPR.4.4.6 HTML PDF PubReader Last 3 months views: 1599	Original Article Eye lens dose survey for medical staff in interventional cardiology: preliminary results Tuyen Nhu Pham, Nham Thi Thuy Nguyen, Nhi Yen Tran, Hoang Anh Ta, Luong Thanh Dang MedPharmRes 2025;9(1):39-48. https://doi.org/10.32895/UMP.MPR.9.1.4 HTML PDF PubReader Last 3 months views: 1564
Original Article Validity and reliability of the Vietnamese version of the readiness for interprofessional learning scale Khoa Duy Duong, Duong Dai Le, Tuong Thi Kim Nguyen, Chung Huynh, Hoang Thi Mai Nguyen, Linh Thuy Khanh Tran, Bao Khac Le MedPharmRes 2025;9(1):74-83. https://doi.org/10.32895/UMP.MPR.9.1.7 HTML PDF PubReader Last 3 months views: 1556	Case Report Reversal of third-degree atrioventricular block in a long-term dialysis patient by temporary transvenous pacing: a case report Minh Duc Dang, Anh My Bui, Dung Tien Nguyen, Chih-Chin Kao, Tu Tuan Tran MedPharmRes 2025;9(1):134-140. https://doi.org/10.32895/UMP.MPR.9.1.12 HTML PDF PubReader Last 3 months views: 1481
Original article Correlation of the Fugl Meyer assessment, Motricity Index and Barthel Index scales in the assessment of rehabilitation in post-stroke patients Duong Thi Huong Nguyen, Dieu Thuong Thi Trinh MedPharmRes 2023;7(4):1-10. https://doi.org/10.32895/UMP.MPR.7.4.1 HTML PDF PubReader Last 3 months views: 1333	Original article The prevalence of insomnia and characteristics of sleep patterns collected from sleep diary among medical students of University of Medicine and Pharmacy at Ho Chi Minh City, Vietnam Phuong Thi Mai, Huyen Thi Bui, Khue Diem Bui MedPharmRes 2021;5(3):34-38. https://doi.org/10.32895/UMP.MPR.5.3.6 HTML PDF PubReader Last 3 months views: 1281

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Original article Virtual Screening, Oriented-synthesis and Evaluation of Lipase Inhibitory Activity of Benzyl Amino Chalcone Derivatives Vu Hoang Minh Trang, Vu Duc Duy, Truong Van Dat, Nguyen Thuy Viet Phuong, Tran Thanh Dao MedPharmRes 2017;1(1):26-36. https://doi.org/10.32895/UMP.MPR.1.1.26/suffix HTML PDF PubReader Cited by 6	Original article Comparing the analgesic efficacy between 100 Hz and 2 Hz electroacupuncture on patients with lumbar osteoarthritis Dieu-Thuong Thi Trinh, Minh-Man Pham Bui, Hong-Nhung Thi Le MedPharmRes 2020;4(3):6-11. https://doi.org/10.32895/UMP.MPR.4.3.2 HTML PDF PubReader Cited by 4
Original article Total oxidant status and total antioxidant capacity in the saliva of patients with chronic periodontitis Thuy Thu Nguyen, Duc Anh Vo, Truc Thanh Thai, Thuy Lam Vo, Nam Cong Nhat Huynh MedPharmRes 2020;4(4):21-26. https://doi.org/10.32895/UMP.MPR.4.4.4 HTML PDF PubReader Cited by 4	Original article Factors relating to preventive practices of health science students during the early stage of the COVID-19 pandemic Giao Huynh, An Le Pham, Vien Truong Nguyen, Thuong Thi Hoai Do, Han Thi Ngoc Nguyen, Dung Dang Nguyen, Thuan Thien Tran MedPharmRes 2020;4(4):27-32. https://doi.org/10.32895/UMP.MPR.4.4.5 HTML PDF PubReader Cited by 4
Original article Phytochemical Screening and Total Phenolics and Flavonoids Contents of Hibiscus Rosa Sinensis. L Cultivated in Viet Nam Truong Thi Han, Le Thi Ly, Tran Thi Minh MedPharmRes 2017;1(1):52-57. https://doi.org/10.32895/UMP.MPR.1.1.52/suffix HTML PDF PubReader Cited by 3	Original article Identification of Curcuma aromatica growing in Vietnam and its potential anticancer components Duc Minh Do, Thanh Hoa Vo, Duc Hanh Nguyen, Kieu Minh Le, Truong Hue Huynh, Thi Do Quyen Le, Thanh Tuan Huynh MedPharmRes 2019;3(3):12-18. https://doi.org/10.32895/UMP.MPR.3.3.3 HTML PDF PubReader Cited by 3
Original article Implementation status of antimicrobial stewardship programs in hospitals: A quantitative analysis study in Ho Chi Minh city, Vietnam Yen Thi Hai Nguyen, Dat Van Truong, Thao Phuong Huynh, Thuong Chi Tang, Chau Van Vinh Nguyen, Thai Minh Tran, Qui Tu Phan, Tien Ngoc Cam Phung, Le Dang Tu Nguyen MedPharmRes 2020;4(2):34-39. https://doi.org/10.32895/UMP.MPR.4.2.5 HTML PDF PubReader Cited by 3	Original article Inhibitory effect of medicinal plants on in vitro human peripheral blood mononuclear cell proliferation, interleukin-2 secretion and antioxidant activity Thuan Thi Minh Nguyen, Nguyen Thi Thao Le MedPharmRes 2021;5(1):22-29. https://doi.org/10.32895/UMP.MPR.5.1.5 HTML PDF PubReader Cited by 3
Original article The Vietnamese version of the constitution in Chinese medicine questionnaire (CCMQ): validity and reliability Duong Thi Huong Nguyen, Thao Thu Le, Huy Khanh Tang, Luu Bao Le, Tien Cam Lam, Linh Thi Hoang Le MedPharmRes 2022;6(2):18-27. https://doi.org/10.32895/UMP.MPR.6.2.3 HTML PDF PubReader Cited by 3	Original article How Vietnamese healthcare students think of nurses: Students stereotypes about Nursing at University of Medicine and Pharmacy at Ho Chi Minh City Tuong Thi Kim Nguyen, Linh Thuy Khanh Tran, Khoa Duy Duong, Tuan Diep Tran MedPharmRes 2023;7(1):39-46. https://doi.org/10.32895/UMP.MPR.7.1.6 HTML PDF PubReader Cited by 3