MedPharmRes

About MedPharmRes

The University of Medicine and Pharmacy at Ho Chi Minh City is pleased to announce its first English journal MedPharmRes (Publication permit 121a/GP-BTTTT of March 23, 2017 by the Ministry of Information and Communications of the Socialist Republic of Vietnam). MedPharmRes is proud to be an English open access peer reviewed journal that delivers cutting edge research in various aspects of medicine, pharmacy, dentistry and other health sciences. Currently, the new permit is numbered 52/GP-BTTTT, issued on March 6, 2024.
Review Article

Sep 30, 2025

Parotitis overview: an integrated approach from classification to treatment strategies

Tran Duc Ky Truong, Chon Nguyen Thanh Ho, Tuan Van Nguyen

MedPharmRes 2025;9(3):275-285.
https://doi.org/10.32895/MPR.25.00014

Parotitis is the inflammation of the largest salivary gland, with diverse aetiologies including infections, autoimmune disorders, and mechanical obstructions. The lack of a standardised classification system, along with varied clinical manifestations, poses significant challenges in diagnosis and management. This review aimed to provide a comprehensive overview of the classification, diagnostic methods, and treatment strategies for parotitis, focusing on both acute and chronic forms. A literature review was conducted using PubMed and Google Sch...
Original Article

Sep 30, 2025

Lynch syndrome in Vietnamese patients with colorectal cancer: prevalence and clinicopathologic characteristics from a single-center study

Cong Bang Huynh, Nien Vinh Lam, Viet Van Ung

MedPharmRes 2025;9(3):286-297.
https://doi.org/10.32895/MPR.25.00005

Introduction: Lynch syndrome (LS) is the most common hereditary cause of colorectal cancer (CRC), but the prevalence and clinical characteristics of this disorder among Vietnamese patients remain underreported. This study estimated the prevalence and described the clinical characteristics of LS in a hospital-based population in Vietnam. Methods: A cross-sectional study on prospective data was conducted at the University Medical Center, Ho Chi Minh City (2022–2024), including 190 CRC participants underwent panel genetic testing for LS-associat...
Original Article

Sep 30, 2025

Source-specific PM2.5 pollution and respiratory health impacts in an urban Asian district: a real-time monitoring study in Ho Chi Minh City, Vietnam

Thuy Thi Truc Phan, Thu Thi Anh Tran, Quang Minh Lam, Tram Thi Hong Huynh, Loan Thi Hong Bui, Dang Ngoc Tran

MedPharmRes 2025;9(3):298-309.
https://doi.org/10.32895/MPR.25.00026

Introduction: Fine particulate matter (PM2.5) is a pressing public health challenge in rapidly urbanizing Asian cities. In District 5 of Ho Chi Minh City, Vietnam, localized PM2.5 pollution arises from diverse sources such as stationary street food vendors, religious temples, traffic congestion, and fuel stations. Understanding the relative contribution of these sources is critical for designing effective interventions. This study aims to identify and quantify the contributions of specific local PM2.5 sources to respiratory health outcomes amon...
Original Article

Sep 30, 2025

Prevalence of hypertension and its related factors among K’Ho ethnic group from 25 to 64 years old at Lien Dam Commune, Di Linh District, Lam Dong Province: a cross-sectional study

Quynh Ho Ngoc Huynh, Thuyet Ka, Phuc Truong Vinh Le

MedPharmRes 2025;9(3):310-321.
https://doi.org/10.32895/MPR.25.00013

Introduction: Hypertension is a major global health concern and a leading cause of preventable mortality. In Vietnam, ethnic minority groups such as the K’Ho may face elevated hypertension risks due to unique cultural practices and socioeconomic disparities. However, little is known about the burden and determinants of hypertension in this population. This study aimed to determine the prevalence of hypertension and examine associated factors among the K’Ho ethnic group in Lien Dam commune, Lam Dong Province. Methods: A cross-sectional study...
Original Article

Sep 30, 2025

Cost-effectiveness analysis of the fixed-dose combination of Dorzolamide+Timolol versus Brinzolamide+Timolol in the treatment of ocular hypertension and primary open-angle glaucoma in Vietnam

Nguyen Thi Hong Tran, Hung Manh Nguyen, Uyen Le Lan Ngo, Chau Thi Khanh Le, Nga Thi Kieu Dang, Nga Thi Quynh Nguyen, Tuan Duc Nguyen, Yen Thi Hai Nguyen

MedPharmRes 2025;9(3):322-333.
https://doi.org/10.32895/MPR.25.00015

Introduction: This pharmacoeconomic assessment aimed to explore the cost-effectiveness of the fixed-dose combination of Dorzolamide+Timolol (DTFC) in ocular hypertension and primary open-angle glaucoma (OH/POAG) in Vietnam. Methods: A cost-effectiveness analysis from third-party health payer perspective was designed with mixed modelling technique to simulate the long-term care for OH/POAG patients in Vietnam. With fixed-dose combination of Brinzolamide+Timolol (BTFC) as comparator, the treatment process was simulated by the decision-tree model ...
Original Article

Sep 30, 2025

Carbapenem resistence and carbapenemase classification of Enterobacteriaceae in intensive care unit: a cross-sectional study

Huong Quynh Nguyen Le, Linh My Le Dang, Ngan Truong Thi Pham, Chuong Van Le, Thanh Kien Lam, Loan Hong Luong, Tuan Minh Huynh

MedPharmRes 2025;9(3):334-346.
https://doi.org/10.32895/MPR.25.00001

Introduction: Carbapenem-resistant Enterobacteriaceae (CRE) poses a significant challenge in treating infections, leading to increased mortality and healthcare burden. Early and accurate identification of CRE is crucial for appropriate antibiotic selection. This study aimed to evaluate the prevalence of CRE isolated from ICU patients and carbapenemase gene profiles among Klebsiella pneumoniae isolates. Methods: A cross-sectional study was conducted on Enterobacteriaceae isolates from 53 ICU patients from March to May 2023. Among 125 initial iso...
Original Article

Sep 30, 2025

Validation of a consumer-grade wearable activity tracker for sleep measurement in Vietnamese patients

Toan Thanh Le, Son Trung Huynh, Xuan-Hieu Thi Nguyen, Vinh Nhu Nguyen, An Le Pham

MedPharmRes 2025;9(3):347-355.
https://doi.org/10.32895/MPR.25.00033

Introduction: The increasing use of wearable activity trackers (WAT) for home-based sleep assessment has raised necessity to clarify their accuracy, particularly in resource-limited settings. This study aimed to validate WAT by polysomnography (PSG) for measuring key sleep parameters—including total sleep time (TST), sleep efficiency (SE), wake after sleep onset (WASO), sleep onset latency (SOL), and sleep stage distribution—in a Vietnamese clinical population, with implications for primary care applications. Methods: This cross-sectional s...
Original Article

Sep 30, 2025

Effectiveness of clinical pharmacist interventions on improving the appropriateness of prescription and treatment outcomes for acute myocardial infarction patients: a before-after study at a Vietnamese hospital

Nhu Quynh Tran, Tan Van Nguyen, Quynh Thi Huong Bui

MedPharmRes 2025;9(3):353-366.
https://doi.org/10.32895/MPR.24.00083

Introduction: Acute myocardial infarction (AMI) is a leading cause of global morbidity and mortality. Clinical pharmacist intervention offers a promising approach to improve prescription appropriateness and treatment outcomes. This study evaluated the impact of this intervention in treatment for AMI patients. Methods: A retrospective before-and-after study was conducted on all AMI patients at the Department of Interventional Cardiology, comparing two phases. The pre phase was designed without clinical pharmacist intervention (August 1, 2019, to...
Original Article

Sep 30, 2025

Discovery of potent inhibitors of NS4B protein of dengue virus type 2 from natural compounds: an in silico approach

Phat Nguyen Pham, Quynh Nguyen Nhu Le, Phuong Thuy Viet Nguyen

MedPharmRes 2025;9(3):367-383.
https://doi.org/10.32895/MPR.24.00072

Introduction: Dengue fever is an annual infectious epidemic disease caused by the Dengue virus, mainly found in tropical and subtropical regions. Of which, Dengue virus type 2 (DENV2) has been a major cause of severe cases globally. Currently, NS4B is one of the promising targets of dengue drug discovery, as it is crucial for the virus life cycle and highly conserved among different dengue strains. However, up till now, no potent synthetic DENV2 NS4B inhibitors have entered clinical research due to toxicity profiles. Therefore, this study aimed...
Original Article

Sep 30, 2025

Listening to auscultation manikins: efficacy of a single simulation training in a resource-limited setting

Bao Quoc Le, Thanh Ngoc Minh Bui, Tan Thi Minh Nguyen, Loi Ngoc Ho, Anh Tuan Pham, Khanh Duc Nguyen, Lam Ho Nguyen, Van Ngoc Thanh Nguyen, Ni Thi Hang Huynh, Ly Thi Truc Ngo, Ngan Kim Tran, Thien Thanh Nguyen, Hanh Thi My Nguyen

MedPharmRes 2025;9(3):384-397.
https://doi.org/10.32895/MPR.25.00003

Introduction: Auscultation proficiency remains suboptimal among healthcare professionals, particularly in resource-limited countries. Simulation-based training is a promising measure to address this gap by offering a safe and controlled environment. This quasi-experimental study aimed to assess the efficacy of Student Auscultation Manikin II® (SAM II®)-based training and to determine the influential factors in our academic setting. Methods: A total of 370 third-year medical students (MSs) received a single 4-hour SAM II®-based training comme...
Case Report

Sep 30, 2025

A case report of pseudohypoaldosteronism type 1 initially misdiagnosed as congenital adrenal hyperplasia in a 3-month-old infant

Lan Thi Chi Huynh, Trung Hieu Nguyen, Trang Thi Thanh Vo

MedPharmRes 2025;9(3):398-403.
https://doi.org/10.32895/MPR.25.00011

Pseudohypoaldosteronism type 1 (PHA1) is a rare and serious disorder caused by aldosterone resistance, leading to significant disturbances in electrolyte balance. Due to overlapping clinical manifestations, it is frequently misidentified as congenital adrenal hyperplasia (CAH), resulting in unnecessary corticosteroid therapy. We reported on the case of a 3-month-old infant who had been initially diagnosed and treated for CAH due to severe salt-wasting symptoms. Further biochemical evaluation and genetic analysis later confirmed PHA1. The patien...
Case Report

Sep 30, 2025

A case report of difficult airway management in patients with severe spinal deformity

Thu Quynh Nguyen Tran, Nghiem Tat Nguyen, Vu Ngoc Phan Ton

MedPharmRes 2025;9(3):404-411.
https://doi.org/10.32895/MPR.25.00036

Airway management in patients with ankylosing spondylitis (AS) poses significant anesthetic challenges, especially in advanced stages characterized by severe spinal deformities, reduced cervical mobility, and fixed flexion contractures. These anatomical limitations complicate tracheal intubation and elevate the risk of airway-related complications. We report a case of a 63-year-old male diagnosed with advanced-stage ankylosing spondylitis (AS), exhibiting a 60-degree fixed thoracolumbar kyphosis and cervical spine ankylosis. The patient who had...
Corrigendum

Sep 30, 2025

Corrigendum: Vaginal fluid creatinine in diagnosing pre-labor rupture of membranes in Vietnam

Thang Viet Ho, Tuan Minh Vo, Nghiem Xuan Huynh, Chau Hai Pham, Hien Dang Phuoc Nguyen, Hanh Thi My Vo

MedPharmRes 2025;9(3):412
https://doi.org/10.32895/UMP.MPR.8.2.9.c

CURRENT ISSUE: Sep 2025, Vol. 9, No. 3

Review Article Parotitis overview: an integrated approach from classification to treatment strategies Tran Duc Ky Truong, Chon Nguyen Thanh Ho, Tuan Van Nguyen MedPharmRes 2025;9(3):275-285. https://doi.org/10.32895/MPR.25.00014 HTML PDF PubReader	Original Article Lynch syndrome in Vietnamese patients with colorectal cancer: prevalence and clinicopathologic characteristics from a single-center study Cong Bang Huynh, Nien Vinh Lam, Viet Van Ung MedPharmRes 2025;9(3):286-297. https://doi.org/10.32895/MPR.25.00005 HTML PDF PubReader
Original Article Source-specific PM2.5 pollution and respiratory health impacts in an urban Asian district: a real-time monitoring study in Ho Chi Minh City, Vietnam Thuy Thi Truc Phan, Thu Thi Anh Tran, Quang Minh Lam, Tram Thi Hong Huynh, Loan Thi Hong Bui, Dang Ngoc Tran MedPharmRes 2025;9(3):298-309. https://doi.org/10.32895/MPR.25.00026 HTML PDF PubReader	Original Article Prevalence of hypertension and its related factors among K’Ho ethnic group from 25 to 64 years old at Lien Dam Commune, Di Linh District, Lam Dong Province: a cross-sectional study Quynh Ho Ngoc Huynh, Thuyet Ka, Phuc Truong Vinh Le MedPharmRes 2025;9(3):310-321. https://doi.org/10.32895/MPR.25.00013 HTML PDF PubReader
Original Article Cost-effectiveness analysis of the fixed-dose combination of Dorzolamide+Timolol versus Brinzolamide+Timolol in the treatment of ocular hypertension and primary open-angle glaucoma in Vietnam Nguyen Thi Hong Tran, Hung Manh Nguyen, Uyen Le Lan Ngo, Chau Thi Khanh Le, Nga Thi Kieu Dang, Nga Thi Quynh Nguyen, Tuan Duc Nguyen, Yen Thi Hai Nguyen MedPharmRes 2025;9(3):322-333. https://doi.org/10.32895/MPR.25.00015 HTML PDF PubReader	Original Article Carbapenem resistence and carbapenemase classification of Enterobacteriaceae in intensive care unit: a cross-sectional study Huong Quynh Nguyen Le, Linh My Le Dang, Ngan Truong Thi Pham, Chuong Van Le, Thanh Kien Lam, Loan Hong Luong, Tuan Minh Huynh MedPharmRes 2025;9(3):334-346. https://doi.org/10.32895/MPR.25.00001 HTML PDF PubReader
Original Article Validation of a consumer-grade wearable activity tracker for sleep measurement in Vietnamese patients Toan Thanh Le, Son Trung Huynh, Xuan-Hieu Thi Nguyen, Vinh Nhu Nguyen, An Le Pham MedPharmRes 2025;9(3):347-355. https://doi.org/10.32895/MPR.25.00033 HTML PDF PubReader	Original Article Effectiveness of clinical pharmacist interventions on improving the appropriateness of prescription and treatment outcomes for acute myocardial infarction patients: a before-after study at a Vietnamese hospital Nhu Quynh Tran, Tan Van Nguyen, Quynh Thi Huong Bui MedPharmRes 2025;9(3):353-366. https://doi.org/10.32895/MPR.24.00083 HTML PDF PubReader
Original Article Discovery of potent inhibitors of NS4B protein of dengue virus type 2 from natural compounds: an in silico approach Phat Nguyen Pham, Quynh Nguyen Nhu Le, Phuong Thuy Viet Nguyen MedPharmRes 2025;9(3):367-383. https://doi.org/10.32895/MPR.24.00072 HTML PDF PubReader	Original Article Listening to auscultation manikins: efficacy of a single simulation training in a resource-limited setting Bao Quoc Le, Thanh Ngoc Minh Bui, Tan Thi Minh Nguyen, Loi Ngoc Ho, Anh Tuan Pham, Khanh Duc Nguyen, Lam Ho Nguyen, Van Ngoc Thanh Nguyen, Ni Thi Hang Huynh, Ly Thi Truc Ngo, Ngan Kim Tran, Thien Thanh Nguyen, Hanh Thi My Nguyen MedPharmRes 2025;9(3):384-397. https://doi.org/10.32895/MPR.25.00003 HTML PDF PubReader
Case Report A case report of pseudohypoaldosteronism type 1 initially misdiagnosed as congenital adrenal hyperplasia in a 3-month-old infant Lan Thi Chi Huynh, Trung Hieu Nguyen, Trang Thi Thanh Vo MedPharmRes 2025;9(3):398-403. https://doi.org/10.32895/MPR.25.00011 HTML PDF PubReader	Case Report A case report of difficult airway management in patients with severe spinal deformity Thu Quynh Nguyen Tran, Nghiem Tat Nguyen, Vu Ngoc Phan Ton MedPharmRes 2025;9(3):404-411. https://doi.org/10.32895/MPR.25.00036 HTML PDF PubReader
Corrigendum Corrigendum: Vaginal fluid creatinine in diagnosing pre-labor rupture of membranes in Vietnam Thang Viet Ho, Tuan Minh Vo, Nghiem Xuan Huynh, Chau Hai Pham, Hien Dang Phuoc Nguyen, Hanh Thi My Vo MedPharmRes 2025;9(3):412 https://doi.org/10.32895/UMP.MPR.8.2.9.c HTML PDF PubReader

AHEAD OF PRINT

Article Prevalence, Colonoscopic Features, and Risk Factors of Colonic Diverticulosis in Vietnamese Adults Undergoing Colonoscopy: A Cross-Sectional Study Uyen Pham-Phuong Vo, Nhu Thi-Hanh Vu, Quang Dinh Le, Doan Thi-Nha Nguyen, Mai Ngoc Luu, Nhung Thi-Hong Ngo, Duc Trong Quach MedPharmRes 2025 [published online ahead of print: Sep 04, 2025] https://doi.org/10.32895/MPR.25.00039 HTML PDF PubReader	Article Trends and Applications of Artificial Intelligence in Competency-Based Education in Medical Programs: A Scoping Review Sang Thanh Do, Cuong Ly To, Quoc Kha Vo Huynh, Duy Thanh Huynh, Song Thi-Thu Nguyen, Phuong Thi-Lan Le MedPharmRes 2025 [published online ahead of print: Aug 22, 2025] https://doi.org/10.32895/MPR.25.00040 HTML PDF PubReader
Article Factors Associated With Pain Management For Trauma Patients In Pre-Hospital Emergency Care In Ho Chi Minh City Quyet Dinh Pham, Trong Duc Nguyen, Loc Vinh Ho Tran, Thuan Doan Nguyen, Thoi Van Nguyen, Nhe Thi Huynh, Nguyet Thi Hoang, Nhi Cam Huynh, Long Duy Nguyen MedPharmRes 2025 [published online ahead of print: Jul 29, 2025] https://doi.org/10.32895/MPR.25.00084 HTML PDF PubReader	Article Diagnosis of endometrioid adenocarcinoma of the fallopian tube misinterpreted as ovarian cancer: a case report Tri Bao Nguyen, Nghiem Xuan Huynh, Hien Thu Thi Pham, Huynh Chi Nguyen MedPharmRes 2025 [published online ahead of print: Jul 29, 2025] https://doi.org/10.32895/MPR.25.00034 HTML PDF PubReader
Article A review of the role of gastric ultrasound in anaesthesia planning for emergency surgery patients Thai Quoc Phan, Thu Pham Minh Ngo, Quan Quang Luu, Khuong Kinh Luu MedPharmRes 2025 [published online ahead of print: Jul 29, 2025] https://doi.org/10.32895/MPR.25.00027 HTML PDF PubReader

MOST READ ARTICLES

Case report A case report of COVID-19-associated severe psychotic symptoms and suicidal behavior: a late psychiatric intervention Yen Phi Ho Nguyen, Xuan Manh Bui, Minh Chau Pham, Anh Ngoc Tran, Trung Nghia Tran, Tich Linh Ngo MedPharmRes 2023;7(s3):s12-s15. https://doi.org/10.32895/UMP.MPR.7.3.S12 HTML PDF PubReader Last 3 months views: 3056	Original Article Auricular acupressure at knee, shenmen, sympathetic, subcortex points increases skin temperature at knee joints: a before-after interventional pilot study Thang Duc Pham, Thi Thi Kim Phan, Tham Ngoc Vo-Nguyen, Hang Thanh Le MedPharmRes 2024;8(3):183-189. https://doi.org/10.32895/UMP.MPR.8.3.20 HTML PDF PubReader Last 3 months views: 2374
Review Transplant tourism: a literature review on development, ethical and law issues Le Chi Cong, Linh Tran, Le Thi Phong Lan, Giang Jan Nguyen, Mohamed Essam Elrggal, Nguyen Hai Nam, Nguyen Tien Huy, Nguyen Duc Truong MedPharmRes 2023;7(1):27-38. https://doi.org/10.32895/UMP.MPR.7.1.5 HTML PDF PubReader Last 3 months views: 2330	Original article Correlation of the Fugl Meyer assessment, Motricity Index and Barthel Index scales in the assessment of rehabilitation in post-stroke patients Duong Thi Huong Nguyen, Dieu Thuong Thi Trinh MedPharmRes 2023;7(4):1-10. https://doi.org/10.32895/UMP.MPR.7.4.1 HTML PDF PubReader Last 3 months views: 1901
Original Article Effects of internet addiction and smartphone addiction on the sleep quality of students of the Faculty of Public Health, University of Medicine and Pharmacy at Ho Chi Minh City in 2023 Minh Quang Lam, Nhat Duyet Pham, Linh Thy Le, Thi Thu Ha Dam MedPharmRes 2025;9(1):62-73. https://doi.org/10.32895/UMP.MPR.9.1.6 HTML PDF PubReader Last 3 months views: 1685	Original Article A retrospective study of the risk factors for linezolid-induced thrombocytopenia in hospitalized patients Khue Nguyen Y Ha, Tuyen Thi Thanh Vu, Truc Thi Thuy Nguyen, Hao Quan Nhu Nguyen, Trang Nguyen Doan Dang MedPharmRes 2025;9(2):207-219. https://doi.org/10.32895/UMP.MPR.9.2.19 HTML PDF PubReader Last 3 months views: 1620
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Original article Total oxidant status and total antioxidant capacity in the saliva of patients with chronic periodontitis Thuy Thu Nguyen, Duc Anh Vo, Truc Thanh Thai, Thuy Lam Vo, Nam Cong Nhat Huynh MedPharmRes 2020;4(4):21-26. https://doi.org/10.32895/UMP.MPR.4.4.4 HTML PDF PubReader Cited by 4	Original article Factors relating to preventive practices of health science students during the early stage of the COVID-19 pandemic Giao Huynh, An Le Pham, Vien Truong Nguyen, Thuong Thi Hoai Do, Han Thi Ngoc Nguyen, Dung Dang Nguyen, Thuan Thien Tran MedPharmRes 2020;4(4):27-32. https://doi.org/10.32895/UMP.MPR.4.4.5 HTML PDF PubReader Cited by 4
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Original article Identification of Curcuma aromatica growing in Vietnam and its potential anticancer components Duc Minh Do, Thanh Hoa Vo, Duc Hanh Nguyen, Kieu Minh Le, Truong Hue Huynh, Thi Do Quyen Le, Thanh Tuan Huynh MedPharmRes 2019;3(3):12-18. https://doi.org/10.32895/UMP.MPR.3.3.3 HTML PDF PubReader Cited by 3	Original article Implementation status of antimicrobial stewardship programs in hospitals: A quantitative analysis study in Ho Chi Minh city, Vietnam Yen Thi Hai Nguyen, Dat Van Truong, Thao Phuong Huynh, Thuong Chi Tang, Chau Van Vinh Nguyen, Thai Minh Tran, Qui Tu Phan, Tien Ngoc Cam Phung, Le Dang Tu Nguyen MedPharmRes 2020;4(2):34-39. https://doi.org/10.32895/UMP.MPR.4.2.5 HTML PDF PubReader Cited by 3
Original article Inhibitory effect of medicinal plants on in vitro human peripheral blood mononuclear cell proliferation, interleukin-2 secretion and antioxidant activity Thuan Thi Minh Nguyen, Nguyen Thi Thao Le MedPharmRes 2021;5(1):22-29. https://doi.org/10.32895/UMP.MPR.5.1.5 HTML PDF PubReader Cited by 3	Original article How Vietnamese healthcare students think of nurses: Students stereotypes about Nursing at University of Medicine and Pharmacy at Ho Chi Minh City Tuong Thi Kim Nguyen, Linh Thuy Khanh Tran, Khoa Duy Duong, Tuan Diep Tran MedPharmRes 2023;7(1):39-46. https://doi.org/10.32895/UMP.MPR.7.1.6 HTML PDF PubReader Cited by 3