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  • 1 : Department of Internal Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Vietnam
  • 2 : Department of Gastroenterology, Gia-Dinh People’s Hospital, Ho Chi Minh City, Vietnam
  • 3 : Department of Diagnostic Imaging, Gia-Dinh People’s Hospital, Ho Chi Minh City, Vietnam
  • 4 : Interventional Radiology Unit, Gia-Dinh People’s Hospital, Ho Chi Minh City, Vietnam

  • Received 24/03/2018
  • Accepted 25/08/2018
  • Available online 22/11/2018
  • 37
  • 692

Budd–Chiari syndrome (BCS), a rare and life-threatening disorder due to hepatic venous outflow obstruction, is occasionally associated with hypoproteinemia. We herein report the first case of BCS with segmental obstruction of the intrahepatic portion of inferior vena cava (IVC) and hepatic veins (HVs) successfully treated by endovascular stenting in Vietnam. A 32-year-old female patient presented with a 2-month history of massive ascites and leg swelling. She refused history of oral contraceptives use. Hepatosplenomegaly without tenderness was noted. Laboratory data showed polycythemia, mild hypoalbuminemia and hypoproteinemia, slightly high total bilirubin and normal transaminase level. The serum ascites albumin gradient was 1.9 g/dL and ascitic protein level was 1.1 g/dL. The other data were normal. BCS was suspected because of the discrepancy between mild liver failure and massive ascites; and the presence of hepatosplenomegaly and polycythemia. On abdominal magnetic resonance imaging, the segmental obstruction of three HVs and IVC was 2-3 cm long without thrombus. Cavogram revealed the severe segmental stenosis of intrahepatic portion of IVC with no visualized HV and extensive collateral veins. A Protégé stent was deployed to IVC. Leg swelling and ascites were completely resolved within 3 days after stenting. During 1-year follow-up, edema was not recurred and repeated laboratory results were all normal.


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