Table 3. Multivariable regression of response rate according to bolus trigger

	Adjusted OR	95%CI	p
CVP < 8mmHg	2.81	1.08 – 7.27	0.033
HR >100	1.89	0.58 – 6.18	0.293
MAP < 65	1.60	0.54 – 4.78	0.840
Lactate > 2 mmol/L	1.27	0.46 – 3.53	0.644
UOP < 0.5 ml/kg/h	1.15	0.41 – 3.27	0.790

Comparision of response rate between CVP < 8 vs ≥ 8 mmHg, HR < 100 vs ≥ 100 bpm, MAP < 65 vs ≥ 65 mmHg, lactate > 2 vs ≤ mmol/L, UOP < 0.5 vs ≥ 0.5 ml/kg/h.
HR: heart rate, UOP: urine output, CVP: central venous pressure, MAP: mean arterial pressure.