Table 1. Clinical data of the ten family members with a confirmed diagnosis of achalasia

Family member	Sex	Beginning of symptoms (years)	Age at diagnosis (years)	Diagnostic method	Treatment method
II7	Female	15 – 20*	59	Symptomatology BE, UGIE	Pneumatic dilatation
III1	Female	15 – 20*	50	Symptomatology BE, UGIE	Pneumatic dilatation
III3	Female	15 – 20*	46	Symptomatology BE, UGIE	Pneumatic dilatation
III17	Female	15 – 20*	54	Symptomatology BE, UGIE	Myotomy surgery
III21	Female	15 – 20*	46	Symptomatology BE, UGIE	Myotomy surgery
III22	Female	15 – 20*	45	Symptomatology BE, UGIE	Myotomy surgery
III24	Female	15 – 20*	42	Symptomatology BE, UGIE	Myotomy surgery
III26	Female	15 – 20*	40	Symptomatology BE, UGIE	Myotomy surgery
IV1	Male	25	28	Symptomatology BE, UGIE	Pneumatic dilatation
IV15	Female	20	30	Symptomatology BE, UGIE	Myotomy surgery

Dysphagia onset was roughly estimated by patients as they were unable to remember the exact age of onset. BE: Barium esophagram; UGIE: upper gastrointestinal endoscopy, F: female, M: male.