Table 1. Case summaries

	Case 1	Case 2	Case 3
Age (years)	61	53	90
Gender	Male	Male	Female
Dose of dabigatran	150 mg BID	150 mg BID	110 mg BID
Last dose of dabigatran (hours)	11	4	10
eGFR (ml/min/1.73 m2)	55	AKI	46
Initial Hb (g/L)	116	143	126
Initital PT (s)	16.7	15.2	14.3
Initial INR	1.33	1.37	1.34
Initial aPTT (seconds)	45.9	50.5	72.2
aPTT post idarucizumab (seconds)	33.7	31.9	33.1
Indication for idarucizumab	Emergency surgery (heart transplant)	Emergency surgery (acute appendicitis)	Life-threatening bleeding (intracranial hemorrhage)
Outcome after idarucizumab administration	Uneventful surgery, discharged	Uneventful surgery, discharged	Repeat CT: No increase of ICH size, only conservative management

Notes: Dabigatran last dose: The time from the last dose of dabigatran to the use of idarucizumab
Abbreviations: eGFR, estimated glomerular rate is estimated MDRD equation; AKI, acute kidney injury; ICH, intracranial haemorrhage; CT, computed tomography.