Table 7. The hydrophobic interactions between the MMP-9 (PDB: 2OW0) and mulberrofuran H during the 20 ns simulations

	Time	Hydrophobic interactions
Complex MMP-9 (PDB: 2OW0) and Mulberrofuran H	0 ns	Benzopyran – His401
		Benzopyran – Leu418
		Benzopyran – Leu397
		Benzopyran – Tyr423
		Tricyclo – Leu188
	5 ns	Benzopyran – Leu397
		Benzopyran – His401
		Benzopyran – Arg424
		Benzopyran – Pro430
		Tricyclo – Leu188
		Tricyclo – Ala189
		Tricyclo – Val398
	10 ns	Benzopyran – His401
		Benzopyran – Tyr423
		Tricyclo – Leu187
	15 ns	Benzopyran – His401
		Benzopyran – Met422
		Benzopyran – Tyr423
		Tricyclo – Leu187
	20 ns	Benzopyran – Leu418
		Benzopyran – His401
		Benzopyran – Arg424
		Benzopyran – Tyr423
		Tricyclo – Leu187