Table 5. Structure, docking score and MIC value on
S. aureus
of synthesized compounds
Compound
R
1
R
2
Docking score (kJ/mol)
Calculating MIC (μg/mL)
Experimental MIC (μg/mL)
HP16
H
p
-C
6
H
4
Cl
-21.40
13.8
4.0
HP17
CH
3
p
-C
6
H
4
Cl
-17.58
29.3
8.0
HP18
H
p
-C
6
H
4
Br
-21.31
14.1
8.0
HP19
CH
3
p
-C
6
H
4
Br
-16.10
39.1
16.0