Table 6. Cytotoxic activity of 2-pyrazoline derivatives

Compound IC50 (μM)
HepG2 RD MDA-MB-231
HP1 22.61 21.95 24.02
HP2 > 100 71.19 > 100
HP3 55.31 32.45 40.61
HP4 63.94 28.81 26.52
HP5 > 100 43.00 53.37
HP6 39.12 24.18 21.68
HP7 41.56 25.50 24.68
HP8 49.92 27.36 26.93
HP9 41.22 26.04 22.03
HP10 26.62 17.74 14.47
HP11 > 100 65.60 67.88
HP12 71.09 39.08 49.31
HP13 > 100 69.03 60.49
HP14 > 100 79.48 95.84
HP15 87.57 53.48 47.30
HP16 64.85 35.56 35.42
HP17 31.02 18.54 19.65
HP18 43.60 23.13 24.12
HP19 73.51 47.05 42.97