Table 3. Analgesic effect on acetic acid-induced writhing response in mice
| Group (n = 8) | Writhing response (time) (Mean ± SD) |
| 0-5 | 6-10 | 11-15 | 16-20 | 21-25 | 26-30 | 31-35 | 36-40 |
| Pathology | 10.6 ± 7.0 | 18.1 ± 4.5 | 18.0 ± 4.2 | 13.1 ± 3.5 | 11.3 ± 4.0 | 9.6 ± 4.9 | 8.0 ± 3.0 | 7.6 ± 5.0 |
| Diclofenac 10 mg/kg | 4.1 ± 4.3 | 8.9 ± 8.3# | 7.9 ± 8.2# | 6.5 ± 6.2# | 5.5 ± 5.7# | 4.5 ± 3.7# | 2.9 ± 3.2## | 2.5 ± 3.0## |
| EEJS 800 mg/kg | 2.4 ± 1.9## | 8.5 ± 5.2## | 6.1 ± 2.5## | 4.3 ± 2.5## | 3.1 ± 3.0## | 3.0 ± 2.8## | 1.9 ± 1.1## | 1.1 ± 0.6## |
| EEJS 1200 mg/kg | 4.0 ± 5.2# | 10.8 ± 9.6 | 9.9 ± 6.3# | 6.8 ± 4.8# | 5.8 ± 3.1# | 5.3 ± 4.3 | 3.4 ± 2.6# | 2.4 ± 2.1# |
p < 0.05,
p < 0.01: compared to the pathology group