Table 1. Compositions of gum basic formulation

No. Ingredients Amount (%) Aims
1 L. brevis NB10 freeze-dried powder (> 109 CFU/g) 10% Provide alive L. brevis NB10 for minimum of 107 CFU/tablet
2 Aerosil 1 - 5% Increase flowability, prevent of gum base aggregation during preparation
3 Xylitol 5 - 20% Diluent, sweetener, help to reduce tooth decay
4 Strawberry flavor powder 0.5 - 3% Flavor
5 Glycerol 0.5 - 2% Softener, adjust the texture feel when chewing
6 Talc 0 - 1.5% Lubricant, increase flowability, prevent the adhesion of gums into tablet press die and punches
7 Magnesium stearate 0 - 1.5% Lubricant, increase flowability, prevent the adhesion of gums into tablet press die and punches
8 HIG04® powder Adjust to total of 100% Binder, gum base, adjust total mass of gum tablet to make chewable mass