Table 3. Effects of treatment on creatinine

	Creatinine (mg/dl)						P2
	Combinaiton groups			Monotherapy groups
	TV (TPV)	△	P1	TV (TPV)	△	P1
T0	0.9 (0.84-0.99)			0.93 (0.88-1.06)			0.024
T1	0.89 (0.83-0.98)	0.01 (-0.02 – 0.03)	0.037	0.93 (0.85-1.03)	0.02 (-0.02 – 0.05)	0.015	0.028
T2	0.89 (0.82-0.98)	0 (-0.03 – 0.04)	0.302	0.95 (0.85-1.01)	0.02 (-0.06 – 0.07)	0.216	0.007
T3	0.89 (0.83-0.98)	0.01 (-0.04 – 0.04)	0.659	0.94 (0.86-1.01)	0.01 (-0.07 – 0.08)	0.482	0.015
T6	0.89 (0.81-0.96)	0.02 (-0.02 – 0.04)	0.006	0.93 (0.88-0.99)	0.01 (-0.05 – 0.09)	0.253	0.006
T9	0.89 (0.81-0.98)	0.01 (-0.04 – 0.07)	0.101	0.92 (0.85-1)	0.05 (-0.07 – 0.1)	0.045	0.056
T12	0.87 (0.8-0.98)	-0.01 (-0.04 – 0.04)	0.910	0.92 (0.85-1)	0.02 (-0.05 – 0.11)	0.033	0.082
T15	0.89 (0.81-0.95)	0.02 (-0.03 – 0.05)	0.062	0.92 (0.83-1.01)	0.03 (-0.05 – 0.12)	0.018	0.027
T18	0.89 (0.82-0.98)	0 (-0.04 – 0.05)	0.412	0.92 (0.84 – 1)	0.02 (-0.08 – 0.13)	0.075	0.074

p1: Wilcoxon test compares the change in each group over time compared to T0
p2: Mann-Whitney test compares the difference between 2 groups at each time point
HBV DNA and post treament