Table 4. Results for respiratory mechanics and oxygenation index at baseline to 48 hours

Variable Absolute difference1) 95%CI p-value
PaO2/FiO2 ratio 81.5 52.7 to 108.6 <0.001
Crs (mL/cmH2O) 3.9 2.0 to 5.9 <0.001
Airway driving pressure (cmH2O) –2.6 –4.0 to –1.35 <0.001
Plateau pressure (cmH2O) –2.5 –3.5 to –1.0 0.001
Esophageal end-expiratory pressure (cmH2O) –1.1 –1.5 to –0.7 <0.001
Transpulmonary end-expiratory pressure (cmH2O) 1.7 1.2 to 2.3 <0.001
The Hodges-Lehmann estimator was utilized to calculate unbiased median differences.
CI, confidence intervals; PaO2, partial pressure of arterial oxygen; FiO2, fraction of inspired oxygen; Crs, compliance respiratory system.