Impact of behavioral health education interventions on knowledge, adherence to treatment, and quality of life of patients with heart failure: A randomized controlled trial

Original Research


Introduction: Heart failure (HF) is a common chronic disease with high morbidity and mortality rates. Besides HF treatments aimed to improve patients’ quality of life and health status, health education interventions for behavioral changes ensuring their adherence to treatment are very important. Therefore, this study aimed to evaluate the effect of behavioral health education interventions on knowledge, treatment adherence, and quality of life of patients with HF.

Methods: This was a randomized controlled trial. A total of 330 patients were selected and randomly distributed into intervention and control groups (n = 165 per group). Data were collected at the time points before the intervention and three months after the intervention using the Dutch Heart Failure Knowledge Scale (DHFKS), Revised Heart Failure Compliance Scale (RHFCS), and quality of life (EQ-5D-5L v2.1, Vietnamese version).

Results: There were no significant differences between the two groups in HF knowledge or quality of life at baseline. After three months of health education intervention, intervention group significant increase to 1.68 times (95%CI: 1.05 – 2.69; p=0.03) in overall HF knowledge; 1.91 times (95%CI: 1.25 – 2.92; p=0.003) in general HF knowledge and 1.59 times (95%CI: 1.03 – 2.45; p=0.038) in behavior of exercise when compare to control group.  However, the quality of life did not change significantly after the intervention.

Conclusions: Although the health education intervention had no impact on the quality of life of patients with HF, it was effective in improving their HF knowledge and treatment adherence.

Graphical abstract